Hiroki Chikumi Selected Research

Lung Neoplasms (Lung Cancer)

3/2014	Synergistic cell growth inhibition by the combination of amrubicin and Akt-suppressing agents in K-ras mutation-harboring lung adenocarcinoma cells: implication of EGFR tyrosine kinase inhibitors.
8/2012	Diagnostic and prognostic impact of serum-soluble UL16-binding protein 2 in lung cancer patients.
4/2012	Lack of AKT activation in lung cancer cells with EGFR mutation is a novel marker of cetuximab sensitivity.
3/2007	Antibody-dependent cellular cytotoxicity mediated by cetuximab against lung cancer cell lines.
3/2007	Diverse activation states of RhoA in human lung cancer cells: contribution of G protein coupled receptors.

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Hiroki Chikumi Research Topics

Disease

6	Asthma (Bronchial Asthma) 01/2017 - 02/2007
5	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 03/2019 - 01/2004
5	Lung Neoplasms (Lung Cancer) 03/2014 - 03/2007
3	Adenocarcinoma of Lung 03/2014 - 03/2005
2	Human Influenza (Influenza) 05/2023 - 08/2021
2	Neoplasms (Cancer) 01/2022 - 11/2012
2	Infections 01/2022 - 12/2021
2	Airway Remodeling 01/2017 - 06/2015
2	Inflammation (Inflammations) 07/2010 - 08/2009
1	Pneumococcal Infections 01/2023
1	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 01/2023
1	Sepsis (Septicemia) 01/2022
1	Empyema 01/2022
1	Pneumonia (Pneumonitis) 01/2022
1	Peritonitis 12/2021
1	Disease Progression 12/2021
1	Communicable Diseases (Infectious Diseases) 09/2020
1	Head and Neck Neoplasms (Head and Neck Cancer) 03/2019
1	Colorectal Neoplasms (Colorectal Cancer) 03/2019
1	Clostridium Infections 01/2018
1	Splenic Infarction 01/2018
1	Chronic Renal Insufficiency 01/2017
1	Anemia 01/2017
1	Respiratory Insufficiency (Respiratory Failure) 04/2015
1	Neoplasm Metastasis (Metastasis) 04/2015
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 03/2014
1	Blast Crisis (Blast Phase) 04/2013
1	Hypertension (High Blood Pressure) 04/2013
1	Leukemia 04/2013
1	Malignant Mesothelioma 11/2012
1	Cardiovascular Diseases (Cardiovascular Disease) 08/2009
1	Disorders of Excessive Somnolence (Hypersomnia) 08/2009
1	Hypoxia (Hypoxemia) 08/2009
1	Obstructive Sleep Apnea 08/2009
1	Respiratory Hypersensitivity 07/2009
1	Rheumatoid Arthritis 08/2007
1	Embolism (Embolus) 08/2007
1	Interstitial Lung Diseases (Interstitial Lung Disease) 08/2007
1	Pulmonary Eosinophilia (Eosinophilic Pneumonia) 01/2006
1	Dyspnea (Shortness of Breath) 01/2006
1	Pruritus (Itching) 01/2006
1	Lung Diseases (Lung Disease) 01/2006

Drug/Important Bio-Agent (IBA)

7	ErbB Receptors (EGF Receptor)IBA 03/2019 - 03/2007
4	Cetuximab (Erbitux)FDA Link 03/2019 - 03/2007
3	Tyrosine Kinase InhibitorsIBA 03/2015 - 04/2012
2	AntigensIBA 05/2023 - 01/2018
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2022 - 12/2021
2	TocotrienolsIBA 01/2017 - 06/2015
2	Erlotinib Hydrochloride (CP 358,774)FDA Link 04/2015 - 03/2015
2	Gefitinib (Iressa)FDA Link 03/2015 - 04/2012
2	Interleukin-2 (IL2)IBA 11/2012 - 03/2007
2	CytokinesIBA 08/2009 - 07/2004
1	HLA-DR Antigens (HLA-DR)IBA 01/2023
1	Inosine Monophosphate (IMP)IBA 01/2022
1	carbapenemaseIBA 01/2022
1	Carbapenems (Carbapenem Antibiotics)IBA 01/2022
1	QuinolonesIBA 01/2022
1	MacrolidesIBA 12/2021
1	Oseltamivir (Tamiflu)FDA Link 08/2021
1	Neuraminidase (Sialidase)IBA 08/2021
1	Monoclonal AntibodiesIBA 03/2019
1	EnzymesIBA 01/2018
1	Ganciclovir (Cytovene)FDA LinkGeneric 01/2018
1	IronIBA 01/2017
1	HematinicsIBA 01/2017
1	Tocopherols (Tocopherol)IBA 06/2015
1	AntioxidantsIBA 06/2015
1	amrubicinIBA 03/2014
1	SaltsIBA 04/2013
1	Rho Guanine Nucleotide Exchange FactorsIBA 04/2013
1	Sirolimus (Rapamycin)FDA Link 09/2012
1	Proteins (Proteins, Gene)FDA Link 08/2012
1	Indicators and Reagents (Reagents)IBA 08/2012
1	Air Pollutants (Pollutants, Air)IBA 06/2012
1	Messenger RNA (mRNA)IBA 08/2009
1	Interleukin-6 (Interleukin 6)IBA 08/2009
1	NF-kappa B (NF-kB)IBA 08/2009
1	OvalbuminIBA 07/2009
1	Leukotriene B4 Receptors (Leukotriene B4 Receptor)IBA 07/2009
1	Leukotriene B4IBA 07/2009
1	Peptides (Polypeptides)IBA 03/2007
1	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 03/2007
1	Guanine NucleotidesIBA 03/2007
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 03/2007
1	GlucocorticoidsIBA 02/2007
1	stearic acid (magnesium stearate)FDA LinkGeneric 01/2006
1	homochlorocyclizine (homochlorcyclizine)IBA 01/2006
1	romidepsin (FK228)FDA Link 03/2005
1	Histone Deacetylase InhibitorsIBA 03/2005

Therapy/Procedure

4	Therapeutics 01/2022 - 01/2004
2	Drug Therapy (Chemotherapy) 09/2020 - 03/2007
1	Hematopoietic Stem Cell Transplantation 01/2023
1	Transplantation 01/2023
1	Bone Marrow Transplantation (Transplantation, Bone Marrow) 01/2023
1	Artificial Respiration (Mechanical Ventilation) 01/2022
1	Central Venous Catheters 01/2022
1	Catheters 12/2021
1	Peritoneal Dialysis 12/2021
1	Chronotherapy 07/2010
1	Biological Therapy 03/2007